Mutants gain unique bonuses. These are different each game.

Voidborne:
(3) Mutants execute targets they damage who are below 20% Health.
(5) And Mutants deal 40% of their damage as true damage.

Bio-Leeching: Your team gains Omnivamp (healing for a percentage of all damage dealt).
(3) 30% Omnivamp
(5) 55% Omnivamp

Voracious Appetite: Mutants grow stronger each time an ally dies.
(3) +20 Attack Damage and Ability Power
(5) +30 Attack Damage and Ability Power

Synaptic Web: The Abilities of Mutants cost less to cast. (Minimum 10 Mana)
(3) 20 Mana less
(5) 40 Mana less
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Adrenaline Rush: Mutants' attacks have a chance to trigger 2 additional attacks against their target.
(3) 40% chance
(5) 75% chance
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Cybernetic Enhancement: Mutants with at least 1 item gain bonus stats.
(3) 450 Health and 30 Attack Damage
(5) 900 Health and 60 Attack Damage

Metamorphosis: Mutants grow every 2 seconds, gaining bonuses that stack up to 5 times.
(3) +18 Armor and Magic Resist, +2 Attack Damage and Ability Power
(5) +25 Armor and Magic Resist, +4 Attack Damage and Ability Power

• 3

  ??? (Randomly selected per game)

• 5

  ??? (Randomly selected per game)

Innate: Colossi are bigger, more powerful, and immune to crowd control effects. However, each Colossus requires 2 team slots.

• 2

  Colossus champions take 25% less damage.

Your team gains bonus maximum Health. Bruisers gain double the bonus.

• 2

  125 Health

• 4

  225 Health

• 6

  400 Health

• 8

  700 Health